the largest city in Michigan and a major Great Lakes port; center of the United States automobile industry; located in southeastern Michigan on the Detroit river across from Windsor | the government agency in the United Kingdom that is responsible for internal security and counterintelligence on British territory |
| the government agency in the United Kingdom that is responsible for internal security and counterintelligence overseas |
| a midwestern state in north central United States in the Great Lakes region, with capital Lansing |
| destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle |