Metis vs mixed-blood

Metis and mixed-blood both are nouns.

Word	Noun	Adjective	Verb	Adverb
Metis	Yes	No	No	No
mixed-blood	Yes	No	No	No

As nouns, mixed-blood is a hypernym of Metis; that is, mixed-blood is a word with a broader meaning than Metis:

Metis: a person in western Canada who is of Caucasian and American Indian ancestry
mixed-blood: a person whose ancestors belonged to two or more racial groups

Metis (noun)	mixed-blood (noun)
a person in western Canada who is of Caucasian and American Indian ancestry	a person whose ancestors belonged to two or more racial groups