Virgin Mary vs Madonna

Virgin Mary and Madonna both are nouns.

Word	Noun	Adjective	Verb	Adverb
Virgin Mary	Yes	No	No	No
Madonna	Yes	No	No	No

As nouns, Virgin Mary and Madonna are synonyms defined as:

Virgin Mary and Madonna: the mother of Jesus; Christians refer to her as the Virgin Mary; she is especially honored by Roman Catholics

Other synonyms of Virgin Mary include Blessed Virgin, Mary, The Virgin.

Virgin Mary (noun)	Madonna (noun)
a Bloody Mary made without alcohol	the mother of Jesus; Christians refer to her as the Virgin Mary; she is especially honored by Roman Catholics
the mother of Jesus; Christians refer to her as the Virgin Mary; she is especially honored by Roman Catholics	United States pop singer and sex symbol during the 1980s (born in 1958)