active site vs situation

active site and situation both are nouns.

Word	Noun	Adjective	Verb	Adverb
active site	Yes	No	No	No
situation	Yes	No	No	No

As nouns, situation is a hypernym of active site; that is, situation is a word with a broader meaning than active site:

active site: the part of an enzyme or antibody where the chemical reaction occurs
situation: physical position in relation to the surroundings

Other hypernyms of active site include site.

active site (noun)	situation (noun)
the part of an enzyme or antibody where the chemical reaction occurs	a job in an organization
	physical position in relation to the surroundings
	the general state of things; the combination of circumstances at a given time
	a condition or position in which you find yourself
	a complex or critical or unusual difficulty