asthenopia vs tiredness

asthenopia and tiredness both are nouns.

Word	Noun	Adjective	Verb	Adverb
asthenopia	Yes	No	No	No
tiredness	Yes	No	No	No

As nouns, tiredness is a hypernym of asthenopia; that is, tiredness is a word with a broader meaning than asthenopia:

asthenopia: a tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem
tiredness: temporary loss of strength and energy resulting from hard physical or mental work

Other hypernyms of asthenopia include fatigue, weariness.

asthenopia (noun)	tiredness (noun)
a tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem	temporary loss of strength and energy resulting from hard physical or mental work