astuteness vs sapience

astuteness and sapience both are nouns.

Word	Noun	Adjective	Verb	Adverb
astuteness	Yes	No	No	No
sapience	Yes	No	No	No

As nouns, sapience is a hypernym of astuteness; that is, sapience is a word with a broader meaning than astuteness:

astuteness: the intellectual ability to penetrate deeply into ideas
sapience: ability to apply knowledge or experience or understanding or common sense and insight

Other hypernyms of astuteness include wisdom.

astuteness (noun)	sapience (noun)
intelligence manifested by being astute (as in business dealings)	ability to apply knowledge or experience or understanding or common sense and insight
the intellectual ability to penetrate deeply into ideas