cachexia vs valetudinarianism

cachexia and valetudinarianism both are nouns.

Word	Noun	Adjective	Verb	Adverb
cachexia	Yes	No	No	No
valetudinarianism	Yes	No	No	No

As nouns, valetudinarianism is a hypernym of cachexia; that is, valetudinarianism is a word with a broader meaning than cachexia:

cachexia: any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease
valetudinarianism: the state of being weak in health or body (especially from old age)

Other hypernyms of cachexia include debility, feebleness, frailness, frailty, infirmity.

cachexia (noun)	valetudinarianism (noun)
any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease	the state of being weak in health or body (especially from old age)