calloused vs thickened

calloused and thickened both are adjectives.

Word	Noun	Adjective	Verb	Adverb
calloused	No	Yes	No	No
thickened	No	Yes	No	No

As adjectives, calloused and thickened are synonyms defined as:

calloused and thickened: having calluses; having skin made tough and thick through wear

Other synonyms of calloused include callous.

calloused (adjective)	thickened (adjective)
having calluses; having skin made tough and thick through wear	made or having become thick
	made thick in consistency
	having calluses; having skin made tough and thick through wear