course of study vs instruction

course of study and instruction both are nouns.

Word	Noun	Adjective	Verb	Adverb
course of study	Yes	No	No	No
instruction	Yes	No	No	No

As nouns, instruction is a hypernym of course of study; that is, instruction is a word with a broader meaning than course of study:

course of study: education imparted in a series of lessons or meetings
instruction: the activities of educating or instructing; activities that impart knowledge or skill

Other hypernyms of course of study include didactics, education, educational activity, pedagogy, teaching.

course of study (noun)	instruction (noun)
education imparted in a series of lessons or meetings	the profession of a teacher
an integrated course of academic studies	the activities of educating or instructing; activities that impart knowledge or skill
	(computer science) a line of code written as part of a computer program
	a message describing how something is to be done