epicene vs effeminate

epicene is a noun but effeminate is not a noun.

Word	Noun	Adjective	Verb	Adverb
epicene	Yes	Yes	No	No
effeminate	No	Yes	No	No

As adjectives, epicene and effeminate are synonyms defined as:

Other synonyms of epicene include cissy, emasculate, sissified, sissy, sissyish.

epicene (noun)	effeminate (noun)
one having both male and female sexual characteristics and organs; at birth an unambiguous assignment of male or female cannot be made

epicene (adjective)	effeminate (adjective)
having an ambiguous sexual identity	having unsuitable feminine qualities
having unsuitable feminine qualities