estrangement vs disaffection

estrangement and disaffection both are nouns.

Word	Noun	Adjective	Verb	Adverb
estrangement	Yes	No	No	No
disaffection	Yes	No	No	No

As nouns, estrangement and disaffection are synonyms defined as:

estrangement and disaffection: the feeling of being alienated from other people

Other synonyms of estrangement include alienation.

estrangement (noun)	disaffection (noun)
the feeling of being alienated from other people	disloyalty to the government or to established authority
separation resulting from hostility	the feeling of being alienated from other people