eyestrain vs tiredness

eyestrain and tiredness both are nouns.

Word	Noun	Adjective	Verb	Adverb
eyestrain	Yes	No	No	No
tiredness	Yes	No	No	No

As nouns, tiredness is a hypernym of eyestrain; that is, tiredness is a word with a broader meaning than eyestrain:

eyestrain: a tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem
tiredness: temporary loss of strength and energy resulting from hard physical or mental work

Other hypernyms of eyestrain include fatigue, weariness.

eyestrain (noun)	tiredness (noun)
a tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem	temporary loss of strength and energy resulting from hard physical or mental work