guardianship vs safekeeping

guardianship and safekeeping both are nouns.

Word	Noun	Adjective	Verb	Adverb
guardianship	Yes	No	No	No
safekeeping	Yes	No	No	No

As nouns, guardianship and safekeeping are synonyms defined as:

guardianship and safekeeping: the responsibility of a guardian or keeper

Other synonyms of guardianship include keeping.

guardianship (noun)	safekeeping (noun)
the responsibility of a guardian or keeper	the responsibility of a guardian or keeper
attention and management implying responsibility for safety