half-blooded vs half-breed

half-blooded is not a noun while half-breed is a noun.

Word	Noun	Adjective	Verb	Adverb
half-blooded	No	Yes	No	No
half-breed	Yes	Yes	No	No

As adjectives, half-blooded and half-breed are synonyms defined as:

half-blooded and half-breed: (of animals) having only one purebred parent

Other synonyms of half-blooded include half-bred.

half-blooded (noun)	half-breed (noun)
	an offensive term for an offspring of parents of different racial group (especially of Caucasian and American Indian ancestry)

half-blooded (adjective)	half-breed (adjective)
(of animals) having only one purebred parent	(of animals) having only one purebred parent