handicap vs injure

handicap is a noun but injure is not a noun.

Word	Noun	Adjective	Verb	Adverb
handicap	Yes	No	Yes	No
injure	No	No	Yes	No

As verbs, injure is a hypernym of handicap; that is, injure is a word with a broader meaning than handicap:

Other hypernyms of handicap include wound.

handicap (noun)	injure (noun)
advantage given to a competitor to equalize chances of winning
something immaterial that interferes with or delays action or progress
the condition of being unable to perform as a consequence of physical or mental unfitness

handicap (verb)	injure (verb)
injure permanently	cause injuries or bodily harm to
put at a disadvantage	cause damage or affect negatively
attempt to forecast the winner (especially in a horse race) and assign odds for or against a contestant	hurt the feelings of