high-energy vs high-powered

high-energy and high-powered both are adjectives.

Word	Noun	Adjective	Verb	Adverb
high-energy	No	Yes	No	No
high-powered	No	Yes	No	No

As adjectives, high-energy and high-powered are synonyms defined as:

Other synonyms of high-energy include high-octane, high-power, high-voltage.

high-energy (adjective)	high-powered (adjective)
of or relating to elementary particles having energies of hundreds of thousands of electron volts	vigorously energetic or forceful
vigorously energetic or forceful	(used of microscopes) capable of a high degree of magnification
providing a relatively large amount of energy upon undergoing a chemical reaction