horoscope vs prognostication

horoscope and prognostication both are nouns.

Word	Noun	Adjective	Verb	Adverb
horoscope	Yes	No	No	No
prognostication	Yes	No	No	No

As nouns, prognostication is a hypernym of horoscope; that is, prognostication is a word with a broader meaning than horoscope:

horoscope: a prediction of someone's future based on the relative positions of the planets
prognostication: a statement made about the future

Other hypernyms of horoscope include forecasting, foretelling, prediction.

horoscope (noun)	prognostication (noun)
a diagram of the positions of the planets and signs of the zodiac at a particular time and place	knowledge of the future (usually said to be obtained from a divine source)
a prediction of someone's future based on the relative positions of the planets	a statement made about the future
	a sign of something about to happen