housecleaning vs cleanup

housecleaning and cleanup both are nouns.

Word	Noun	Adjective	Verb	Adverb
housecleaning	Yes	No	No	No
cleanup	Yes	No	No	No

As nouns, cleanup is a hypernym of housecleaning; that is, cleanup is a word with a broader meaning than housecleaning:

Other hypernyms of housecleaning include cleaning, cleansing.

housecleaning (noun)	cleanup (noun)
the act of cleaning the rooms and furnishings of a house	the act of making something clean
(figurative) the act of reforming by the removal of unwanted personnel or practices or conditions	(baseball) the fourth position in the batting order (usually filled by the best batter on the team)
	a very large profit