indignation vs ire

indignation and ire both are nouns.

Word	Noun	Adjective	Verb	Adverb
indignation	Yes	No	No	No
ire	Yes	No	No	No

As nouns, ire is a hypernym of indignation; that is, ire is a word with a broader meaning than indignation:

indignation: a feeling of righteous anger
ire: a strong emotion; a feeling that is oriented toward some real or supposed grievance

Other hypernyms of indignation include anger, choler.

indignation (noun)	ire (noun)
a feeling of righteous anger	belligerence aroused by a real or supposed wrong (personified as one of the deadly sins)
	a strong emotion; a feeling that is oriented toward some real or supposed grievance