irritable vs nettlesome

irritable and nettlesome both are adjectives.

Word	Noun	Adjective	Verb	Adverb
irritable	No	Yes	No	No
nettlesome	No	Yes	No	No

As adjectives, irritable and nettlesome are synonyms defined as:

Other synonyms of irritable include cranky, fractious, peckish, peevish, pettish, petulant, scratchy, techy, testy, tetchy.

irritable (adjective)	nettlesome (adjective)
easily irritated or annoyed	causing irritation or annoyance
capable of responding to stimuli	easily irritated or annoyed
abnormally sensitive to a stimulus