irritate vs antagonize

irritate and antagonize both are verbs.

Word	Noun	Adjective	Verb	Adverb
irritate	No	No	Yes	No
antagonize	No	No	Yes	No

As verbs, antagonize is a hyponym of irritate; that is, antagonize is a word with a more specific, narrower meaning than irritate:

irritate (verb)	antagonize (verb)
excite to an abnormal condition, or chafe or inflame	provoke the hostility of
excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus	act in opposition to
cause annoyance in; disturb, especially by minor irritations