keratodermia vs skin disease

keratodermia and skin disease both are nouns.

Word	Noun	Adjective	Verb	Adverb
keratodermia	Yes	No	No	No
skin disease	Yes	No	No	No

As nouns, skin disease is a hypernym of keratodermia; that is, skin disease is a word with a broader meaning than keratodermia:

Other hypernyms of keratodermia include disease of the skin, skin disorder.

keratodermia (noun)	skin disease (noun)
any skin disorder consisting of a growth that appears horny	a disease affecting the skin