lesson vs instruction

lesson and instruction both are nouns.

Word	Noun	Adjective	Verb	Adverb
lesson	Yes	No	No	No
instruction	Yes	No	No	No

As nouns, instruction is a hypernym of lesson; that is, instruction is a word with a broader meaning than lesson:

Other hypernyms of lesson include pedagogy, teaching.

lesson (noun)	instruction (noun)
a task assigned for individual study	the profession of a teacher
a unit of instruction	the activities of educating or instructing; activities that impart knowledge or skill
punishment intended as a warning to others	(computer science) a line of code written as part of a computer program
the significance of a story or event	a message describing how something is to be done