lousiness vs infestation

lousiness and infestation both are nouns.

Word	Noun	Adjective	Verb	Adverb
lousiness	Yes	No	No	No
infestation	Yes	No	No	No

As nouns, infestation is a hypernym of lousiness; that is, infestation is a word with a broader meaning than lousiness:

lousiness: infestation with lice (Pediculus humanus) resulting in severe itching
infestation: the state of being invaded or overrun by parasites

lousiness (noun)	infestation (noun)
the quality of being disgusting to the senses or emotions	a swarm of insects that attack plants
infestation with lice (Pediculus humanus) resulting in severe itching	the state of being invaded or overrun by parasites