make-up vs karyotype

make-up and karyotype both are nouns.

Word	Noun	Adjective	Verb	Adverb
make-up	Yes	No	No	No
karyotype	Yes	No	No	No

As nouns, karyotype is a hyponym of make-up; that is, karyotype is a word with a more specific, narrower meaning than make-up:

make-up: the way in which someone or something is composed
karyotype: the appearance of the chromosomal makeup of a somatic cell in an individual or species (including the number and arrangement and size and structure of the chromosomes)

Other hyponyms of make-up include structure, phenotype, genetic constitution, genotype, grain, texture.

make-up (noun)	karyotype (noun)
cosmetics applied to the face to improve or change your appearance	the appearance of the chromosomal makeup of a somatic cell in an individual or species (including the number and arrangement and size and structure of the chromosomes)
the way in which someone or something is composed
an event that is substituted for a previously cancelled event