malignance vs disease

malignance and disease both are nouns.

Word	Noun	Adjective	Verb	Adverb
malignance	Yes	No	No	No
disease	Yes	No	No	No

As nouns, disease is a hypernym of malignance; that is, disease is a word with a broader meaning than malignance:

malignance: (medicine) a malignant state; progressive and resistant to treatment and tending to cause death
disease: an impairment of health or a condition of abnormal functioning

malignance (noun)	disease (noun)
quality of being disposed to evil; intense ill will	an impairment of health or a condition of abnormal functioning
(medicine) a malignant state; progressive and resistant to treatment and tending to cause death