manuscript vs leaf-book

manuscript and leaf-book both are nouns.

Word	Noun	Adjective	Verb	Adverb
manuscript	Yes	No	No	No
leaf-book	Yes	No	No	No

As nouns, leaf-book is a hyponym of manuscript; that is, leaf-book is a word with a more specific, narrower meaning than manuscript:

manuscript: handwritten book or document
leaf-book: an unbound manuscript of some ancient classic (as distinguished from a scroll)

Other hyponyms of manuscript include codex, palimpsest, roll, scroll.

manuscript (noun)	leaf-book (noun)
the form of a literary work submitted for publication	an unbound manuscript of some ancient classic (as distinguished from a scroll)
handwritten book or document