mastectomy vs extirpation

mastectomy and extirpation both are nouns.

Word	Noun	Adjective	Verb	Adverb
mastectomy	Yes	No	No	No
extirpation	Yes	No	No	No

As nouns, extirpation is a hypernym of mastectomy; that is, extirpation is a word with a broader meaning than mastectomy:

Other hypernyms of mastectomy include ablation, cutting out, excision.

mastectomy (noun)	extirpation (noun)
surgical removal of a breast to remove a malignant tumor	surgical removal of a body part or tissue
	the act of pulling up or out; uprooting; cutting off from existence