of course vs naturally

of course and naturally both are adverbs.

Word	Noun	Adjective	Verb	Adverb
of course	No	No	No	Yes
naturally	No	No	No	Yes

As adverbs, of course and naturally are synonyms defined as:

Other synonyms of of course include course.

of course (adverb)	naturally (adverb)
as might be expected	as might be expected
	according to nature; by natural means; without artificial help
	in a natural or normal manner
	through inherent nature