powerful vs efficacious

powerful and efficacious both are adjectives.

Word	Noun	Adjective	Verb	Adverb
powerful	No	Yes	No	Yes
efficacious	No	Yes	No	No

powerful (adjective)	efficacious (adjective)
having great power or force or potency or effect	marked by qualities giving the power to produce an intended effect
having great influence	producing or capable of producing an intended result or having a striking effect
displaying superhuman strength or power
(of a person) possessing physical strength and weight; rugged and powerful
strong enough to knock down or overwhelm

powerful (adverb)	efficacious (adverb)
(Southern regional intensive) very; to a great degree