prohibition vs refusal

prohibition and refusal both are nouns.

Word	Noun	Adjective	Verb	Adverb
prohibition	Yes	No	No	No
refusal	Yes	No	No	No

As nouns, refusal is a hypernym of prohibition; that is, refusal is a word with a broader meaning than prohibition:

prohibition (noun)	refusal (noun)
the action of prohibiting or inhibiting or forbidding (or an instance thereof)	a message refusing to accept something that is offered
a decree that prohibits something	the act of refusing
refusal to approve or assent to
a law forbidding the sale of alcoholic beverages
the period from 1920 to 1933 when the sale of alcoholic beverages was prohibited in the United States by a constitutional amendment