prostration vs malady

prostration and malady both are nouns.

Word	Noun	Adjective	Verb	Adverb
prostration	Yes	No	No	No
malady	Yes	No	No	No

As nouns, malady is a hypernym of prostration; that is, malady is a word with a broader meaning than prostration:

prostration: an abrupt failure of function or complete physical exhaustion
malady: impairment of normal physiological function affecting part or all of an organism

Other hypernyms of prostration include illness, sickness, unwellness.

prostration (noun)	malady (noun)
the act of assuming a prostrate position	impairment of normal physiological function affecting part or all of an organism
abject submission; the emotional equivalent of prostrating your body	any unwholesome or desperate condition
an abrupt failure of function or complete physical exhaustion