region vs southland

region and southland both are nouns.

Word	Noun	Adjective	Verb	Adverb
region	Yes	No	No	No
southland	Yes	No	No	No

As nouns, southland is a hyponym of region; that is, southland is a word with a more specific, narrower meaning than region:

region (noun)	southland (noun)
a part of an animal that has a special function or is supplied by a given artery or nerve	any region lying in or toward the south
a knowledge domain that you are interested in or are communicating about
the extended spatial location of something
a large indefinite location on the surface of the Earth
the approximate amount of something (usually used prepositionally as in `in the region of')