resignation vs despair

resignation and despair both are nouns.

Word	Noun	Adjective	Verb	Adverb
resignation	Yes	No	No	No
despair	Yes	No	Yes	No

As nouns, despair is a hypernym of resignation; that is, despair is a word with a broader meaning than resignation:

resignation: acceptance of despair
despair: the feeling that everything is wrong and nothing will turn out well

resignation (noun)	despair (noun)
the act of giving up (a claim or office or possession etc.)	the feeling that everything is wrong and nothing will turn out well
a formal document giving notice of your intention to resign	a state in which all hope is lost or absent
acceptance of despair

resignation (verb)	despair (verb)
	abandon hope; give up hope; lose heart