route vs thoroughfare

route and thoroughfare both are nouns.

Word	Noun	Adjective	Verb	Adverb
route	Yes	No	Yes	No
thoroughfare	Yes	No	No	No

As nouns, thoroughfare is a hyponym of route; that is, thoroughfare is a word with a more specific, narrower meaning than route:

route (noun)	thoroughfare (noun)
an open way (generally public) for travel or transportation	a public road from one place to another
an established line of travel or access

route (verb)	thoroughfare (verb)
send via a specific route
divert in a specified direction
send documents or materials to appropriate destinations