self-annihilation vs self-destruction

self-annihilation and self-destruction both are nouns.

Word	Noun	Adjective	Verb	Adverb
self-annihilation	Yes	No	No	No
self-destruction	Yes	No	No	No

As nouns, self-annihilation and self-destruction are synonyms defined as:

Other synonyms of self-annihilation include suicide.

self-annihilation (noun)	self-destruction (noun)
the act of killing yourself	the act of killing yourself
	the act of destroying yourself