senioritis vs tiredness

senioritis and tiredness both are nouns.

Word	Noun	Adjective	Verb	Adverb
senioritis	Yes	No	No	No
tiredness	Yes	No	No	No

As nouns, tiredness is a hypernym of senioritis; that is, tiredness is a word with a broader meaning than senioritis:

senioritis: tiredness with the final year of high school
tiredness: temporary loss of strength and energy resulting from hard physical or mental work

Other hypernyms of senioritis include fatigue, weariness.

senioritis (noun)	tiredness (noun)
tiredness with the final year of high school	temporary loss of strength and energy resulting from hard physical or mental work