single out vs isolate

single out and isolate both are verbs.

Word	Noun	Adjective	Verb	Adverb
single out	No	No	Yes	No
isolate	No	No	Yes	No

As verbs, isolate is a hyponym of single out; that is, isolate is a word with a more specific, narrower meaning than single out:

Other hyponyms of single out include insulate, hive off, segregate, redline, disadvantage, disfavor, disfavour.

single out (verb)	isolate (verb)
select from a group	place or set apart
treat differently on the basis of sex or race	obtain in pure form
	set apart from others
	separate (experiences) from the emotions relating to them