title role vs persona

title role and persona both are nouns.

Word	Noun	Adjective	Verb	Adverb
title role	Yes	No	No	No
persona	Yes	No	No	No

As nouns, persona is a hypernym of title role; that is, persona is a word with a broader meaning than title role:

Other hypernyms of title role include character, part, role, theatrical role.

title role (noun)	persona (noun)
the role of the character after whom the play is named	(Jungian psychology) a personal facade that one presents to the world
	an actor's portrayal of someone in a play