uptight vs high-strung

uptight and high-strung both are adjectives.

Word	Noun	Adjective	Verb	Adverb
uptight	No	Yes	No	No
high-strung	No	Yes	No	No

As adjectives, uptight and high-strung are synonyms defined as:

Other synonyms of uptight include edgy, highly strung, jittery, jumpy, nervy, overstrung, restive.

uptight (adjective)	high-strung (adjective)
being in a tense state	being in a tense state