vacuolization vs American spelling

vacuolization and American spelling both are nouns.

Word	Noun	Adjective	Verb	Adverb
vacuolization	Yes	No	No	No
American spelling	Yes	No	No	No

vacuolization (noun)	American spelling (noun)
the state of having become filled with vacuoles	English orthography used in the United States (characterized by 'analyze', 'center', 'usable')