vanity vs worthlessness

vanity and worthlessness both are nouns.

Word	Noun	Adjective	Verb	Adverb
vanity	Yes	No	No	No
worthlessness	Yes	No	No	No

As nouns, worthlessness is a hypernym of vanity; that is, worthlessness is a word with a broader meaning than vanity:

Other hypernyms of vanity include ineptitude.

vanity (noun)	worthlessness (noun)
low table with mirror or mirrors where one sits while dressing or applying makeup	having no qualities that would render it valuable or useful
the trait of being unduly vain and conceited; false pride	the quality of being without practical use
the quality of being valueless or futile
feelings of excessive pride