weakness vs predilection

weakness and predilection both are nouns.

Word	Noun	Adjective	Verb	Adverb
weakness	Yes	No	No	No
predilection	Yes	No	No	No

As nouns, predilection is a hypernym of weakness; that is, predilection is a word with a broader meaning than weakness:

Other hypernyms of weakness include penchant, preference, taste.

weakness (noun)	predilection (noun)
the property of lacking physical or mental strength; liability to failure under pressure or stress or strain	a predisposition in favor of something
powerlessness revealed by an inability to act	a strong liking
a penchant for something even though it might not be good for you
a flaw or weak point
the condition of being financially weak