departure vs loss

departure and loss both are nouns.

Word	Noun	Adjective	Verb	Adverb
departure	Yes	No	No	No
loss	Yes	No	No	No

As nouns, departure and loss are synonyms defined as:

Other synonyms of departure include exit, expiration, going, passing, release.

departure (noun)	loss (noun)
the act of departing	the act of losing someone or something
euphemistic expressions for death	the disadvantage that results from losing something
a variation that deviates from the standard or norm	military personnel lost by death or capture
	the experience of losing a loved one
	euphemistic expressions for death
	the amount by which the cost of a business exceeds its revenue
	something that is lost
	gradual decline in amount or activity