loss vs departure

loss and departure both are nouns.

Word	Noun	Adjective	Verb	Adverb
loss	Yes	No	No	No
departure	Yes	No	No	No

As nouns, loss and departure are synonyms defined as:

Other synonyms of loss include exit, expiration, going, passing, release.

loss (noun)	departure (noun)
the act of losing someone or something	the act of departing
the disadvantage that results from losing something	euphemistic expressions for death
military personnel lost by death or capture	a variation that deviates from the standard or norm
the experience of losing a loved one
euphemistic expressions for death
the amount by which the cost of a business exceeds its revenue
something that is lost
gradual decline in amount or activity