depletion vs using up

depletion and using up both are nouns.

Word	Noun	Adjective	Verb	Adverb
depletion	Yes	No	No	No
using up	Yes	No	No	No

As nouns, using up is a hyponym of depletion; that is, using up is a word with a more specific, narrower meaning than depletion:

Other hyponyms of depletion include consumption, expenditure, exhaustion, drain.

depletion (noun)	using up (noun)
the act of decreasing something markedly	the act of consuming something
the state of being depleted