using up vs depletion

using up and depletion both are nouns.

Word	Noun	Adjective	Verb	Adverb
using up	Yes	No	No	No
depletion	Yes	No	No	No

As nouns, depletion is a hypernym of using up; that is, depletion is a word with a broader meaning than using up:

using up (noun)	depletion (noun)
the act of consuming something	the act of decreasing something markedly
	the state of being depleted