despicable vs wretched

despicable and wretched both are adjectives.

Word	Noun	Adjective	Verb	Adverb
despicable	No	Yes	No	No
wretched	No	Yes	No	No

As adjectives, despicable and wretched are synonyms defined as:

Other synonyms of despicable include slimy, ugly, unworthy, vile, worthless.

despicable (adjective)	wretched (adjective)
morally reprehensible	morally reprehensible
	of very poor quality or condition
	characterized by physical misery
	deserving or inciting pity
	very unhappy; full of misery