disrespect vs offend

disrespect is a noun but offend is not a noun.

Word	Noun	Adjective	Verb	Adverb
disrespect	Yes	No	Yes	No
offend	No	No	Yes	No

As verbs, offend is a hyponym of disrespect; that is, offend is a word with a more specific, narrower meaning than disrespect:

Other hyponyms of disrespect include breach, break, go against, infract, transgress, violate.

disrespect (noun)	offend (noun)
a manner that is generally disrespectful and contemptuous
a disrespectful mental attitude
an expression of lack of respect

disrespect (verb)	offend (verb)
have little or no respect for; hold in contempt	hurt the feelings of
show a lack of respect for	cause to feel resentment or indignation
	strike with disgust or revulsion
	act in disregard of laws, rules, contracts, or promises