genotype vs make-up

genotype and make-up both are nouns.

Word	Noun	Adjective	Verb	Adverb
genotype	Yes	No	No	No
make-up	Yes	No	No	No

As nouns, make-up is a hypernym of genotype; that is, make-up is a word with a broader meaning than genotype:

Other hypernyms of genotype include composition, constitution, makeup, physical composition.

genotype (noun)	make-up (noun)
the particular alleles at specified loci present in an organism	cosmetics applied to the face to improve or change your appearance
a group of organisms sharing a specific genetic constitution	the way in which someone or something is composed
	an event that is substituted for a previously cancelled event